Israel Journal of Chemistry

1??Phenylcycloakylamine Derivatives I

A Kalir, Z Pelah

Index: Kalir,A.; Pelah,K. Israel Journal of Chemistry, 1967 , vol. 5, p. 223 - 229

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Citation Number: 17

Abstract

I-Phenyl substituted cyclobutyl-, cyclopcutyl-. and cyclohexylarmncs were obtained in the Hofmann reaction of I-phenylcycloalkanecarboxamides. l-Phenylcyclohexylamine was also prepared by the Ritter reaction of I-phenylcyclohexanol. ... A series of phenylcycloalkyl derivatives were prepared for pharmacological eva.luation't? from the appropriate I-phenylcycloalkyl cyanides according to the following scheme (A, n = 5; Br, n= 4; C, n = 3). ... Ph~. COOMe MeOH HCIPh. c. ...

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