Synthesis of ortho??substituted benzophenones by way of benzophenones carrying A t??butyl group as a blocking group

PS Hofman, DJ Reiding…

Index: Hofman,P.S. et al. Recueil des Travaux Chimiques des Pays-Bas, 1960 , vol. 79, p. 790 - 793

Full Text: HTML

Citation Number: 9

Abstract

Abstract Whereas benzoylation of toluene or m-xylene is known to lead to a mixture of 2-and 4-methylbenzophenone and to 2, 4-dimethylbenzophenone respectively, the presence of a blocking t. butyl group in the 4-and the 5-positions respectively leads to products which on debutylation yield benzophenones with substituents in the ortho position only.

Related Articles:

Facile access to sterically hindered aryl ketones via carbonylative cross-coupling: application to the total synthesis of luteolin

[O'Keefe, B. Michael; Simmons, Nicholas; Martin, Stephen F. Tetrahedron, 2011 , vol. 67, # 24 p. 4344 - 4351]

Synthesis of Ketones from α??Oxocarboxylates and Aryl Bromides by Cu/Pd??Catalyzed Decarboxylative Cross??Coupling

[Goossen, Lukas J.; Rudolphi, Felix; Oppel, Christoph; Rodriguez, Nuria Angewandte Chemie - International Edition, 2008 , vol. 47, # 16 p. 3043 - 3045]

Carbonylative Cross-Coupling of ortho-Disubstituted Aryl Iodides. Convenient Synthesis of Sterically Hindered Aryl Ketones

[Michael O'Keefe; Simmons, Nicholas; Martin, Stephen F. Organic Letters, 2008 , vol. 10, # 22 p. 5301 - 5304]

Aluminum dodecatungstophosphate (AlPW 12 O 40) as a non-hygroscopic Lewis acid catalyst for the efficient Friedel–Crafts acylation of aromatic compounds under …

[Firouzabadi, Habib; Iranpoor, Nasser; Nowrouzi, Farhad Tetrahedron, 2004 , vol. 60, # 48 p. 10843 - 10850]

Synthesis of substituted benzophenones by a direct condensation of substituted benzoic acids with benzene in the presence of aluminium chloride

[Reiding,D.J.; Nauta,W.T. Recueil des Travaux Chimiques des Pays-Bas, 1961 , vol. 80, p. 399 - 402]

More Articles...