Bioavailability and catabolism of green tea flavan-3-ols in humans

Daniele Del Rio, Luca Calani, Chiara Cordero, Sara Salvatore, Nicoletta Pellegrini, Furio Brighenti, Daniele Del Rio, Luca Calani, Chiara Cordero, Sara Salvatore, Nicoletta Pellegrini, Furio Brighenti, Daniele Del Rio, Luca Calani, Chiara Cordero, Sara Salvatore, Nicoletta Pellegrini, Furio Brighenti

Index: Nutrition 26(11-12) , 1110-6, (2010)

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Abstract

Objective The aim of this study was to investigate green tea flavan-3-ol catabolism and plasma pharmacokinetic and urinary excretion by high-performance liquid chromatography with tandem mass spectrometry to evaluate their absolute bioavailability by taking into account all known and some unknown catabolites deriving from their interaction with the gastrointestinal tract and its host microflora.