2-Diethylaminoethyl esters of 1, 3-disubstituted propane-2-carboxylic acids

V Valenta, J Holubek, E Svátek, V Miller…

Index: Valenta, Vladimir; Holubek, Jiri; Svatek, Emil; Miller, Vladimir; Vlkova, Marie; Protiva, Miroslav Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 10 p. 2534 - 2544

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Citation Number: 2

Abstract

Abstract Alkaline hydrolysis of diethyl 1-(tetrahydro-2-furyl)-3-(1-naphthyl) propane-2, 2- dicarboxylate (IV) gave the crude acid V which was purified via the dipotassium salt and was obtained as the homogeneous higher melting crystal form. Its thermic decarboxylation yielded the acid II as a mixture of two racemates (38: 62); crystallization led to the almost homogeneous racemate B (10: 90). Reaction of the sodium salt of II with dimethyl sulfate ...