Urotropin synthesis of 3, 5-di-tert-butylsalicylic acid derivatives
VB Vol'eva, IS Belostotskaya, NL Komissarova…
Index: Vol'eva; Belostotskaya; Komissarova; Kurkovskaya; Pleshakova; Prokofeva Russian Journal of Organic Chemistry, 2007 , vol. 43, # 10 p. 1488 - 1491
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Abstract
Abstract The stability of 3, 5-di-tert-butylsalicylic aldehyde against oxidation is due to autoinhibiting of the chain process. However its oxidation into 3, 5-di-tert-butylsalicylic acid was performed at the use of acetyl protection of the hydroxy group. In reaction of 6-bromo-2, 4-di-tert-butylphenol with urotropin the formation was discovered of 3, 5-di-tert-butylsalicylic acid, its nitrile and amide.
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