A Practical Route to Regiospecifically Substituted (R)??and (S)??Oxazolylphenols

…, P Mosset, W Bauer, RW Saalfrank

Index: Scheurer, Andreas; Mosset, Paul; Bauer, Walter; Saalfrank, Rolf W. European Journal of Organic Chemistry, 2001 , # 16 p. 3067 - 3074

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Citation Number: 11

Abstract

Abstract New, diversely substituted phenolic oxazolines 14a− d and 15a− d were prepared by two complementary routes A and B, starting from salicylic derivatives 4− 7 and various enantiomerically pure 1, 2-amino alcohols 13a− d. In route A, the 1, 2-amino alcohols 13a− d were directly condensed with the salicylic acids 5 and 7, using the Appel reaction, whereas in route B the amino alcohols 13b− d were treated with the 2- ...