Discovery of 14??3??3 Protein–Protein Interaction Inhibitors that Sensitize Multidrug??Resistant Cancer Cells to Doxorubicin and the Akt Inhibitor GSK690693

M Mori, G Vignaroli, Y Cau, J Dinić, R Hill…

Index: ChemMedChem, , vol. 9, # 5 p. 973 - 983

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Citation Number: 9

Abstract

... ChemMedChem, 9: 973–983. ... Volume: Issue: Page ... Both 9 and 10 exerted moderate cell growth inhibitory effects in NCI-H460 (Figure 5 A) and NCI-H460/R cells (Figure 5 B). The addition of compounds 9 or 10 (each at 10 μM) to doxorubicin (DOX) improved the effect of DOX in ...

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