Synlett

Cerium (III)-catalyzed addition of diethylzinc to carbonyl compounds

S Fischer, U Groth, M Jeske, T Schütz

Index: Fischer, Stefan; Groth, Ulrich; Jeske, Mario; Schuetz, Thorben Synlett, 2002 , # 11 p. 1922 - 1924

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Citation Number: 3

Abstract

Abstract CeCl 3 catalyzes the addition of Et 2 Zn to a variety of alipahtic and aromatic aldehydes and ketones in THF in the presence of TMSCl as a scavenger. Optimization of the applied solvent allowed to avoid the TMSCl mediated addition using CeCl 3·(THF) 2 or Ce (i- PrO) 3 as catalysts. This represents the first application of lanthanide compounds for the addition of Et 2 Zn to carbonyl compounds.

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