Protection of Hydroxyl Groups as a Trimethylsilyl Ether by 1, 1, 1, 3, 3, 3-Hexamethyldisilazane Promoted by Aspartic Acid as an Efficient Organocatalyst
A Ghorbani-Choghamarani, M Norouzi
Index: Ghorbani-Choghamarani, Arash; Norouzi, Masoomeh Chinese Journal of Catalysis, 2011 , vol. 32, # 3-4 p. 595 - 598
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Abstract
Abstract A wide variety of alcohols and phenols were protected as trimethylsilyl ethers using 1, 1, 1, 3, 3, 3-hexamethyl disilazane catalyzed by aspartic acid as a non-toxic, metal-free, and green organocatalyst at room temperature in acetonitrile under mild and heterogeneous conditions. The procedure is operationally simple and the silylated product was obtained in high yield and purity.
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