A Convenient Method for the Synthesis of N-Free 5'-O-(p, p'-Dimethoxytrityl)-2'-deoxyribonucleosides via the 5'-O-Selective Tritylation of the Parent Substances
M Kataoka, Y Hayakawa
Index: Kataoka, Masanori; Hayakawa, Yoshihiro Journal of Organic Chemistry, 1999 , vol. 64, # 16 p. 6087 - 6089
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Citation Number: 14
Abstract
5′-O-(p, p′-Dimethoxytrityl)-2′-deoxyribonucleosides without protection of the amino functions, 5-8, are important substances for the synthesis of various kinds of nucleic acid- related derivatives. For example, these compounds are useful as building blocks for oligonucleotide synthesis via the hydroxyl-activation method. 1 They have also served as key intermediates of N-free nucleoside-3′-phosphoramidites2, 3 and-H-phosphonates, 4 ...
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