Tetrahedron Letters

A novel method for bromodecarboxylation of α, β-unsaturated carboxylic acids using catalytic sodium nitrite

VN Telvekar, BS Takale

Index: Telvekar, Vikas N.; Takale, Balaram S. Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2394 - 2396

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Citation Number: 12

Abstract

A first novel synthetic utility of catalytic sodium nitrite in combination with aqueous HBr, for bromo decarboxylation of α, β-unsaturated carboxylic acid is described. α, β-Unsaturated carboxylic acid compounds successfully converted into corresponding bromo compounds. The advantages of this protocol are shorter reaction time and moderate to good yields.

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