An Efficient, Overall [4+ 1] Cycloadditon of 1, 3??Dienes and Nitrene Precursors

Q Wu, J Hu, X Ren, JS Zhou

Index: Wu, Qiong; Hu, Jian; Ren, Xinfeng; Zhou, Jianrong Chemistry - A European Journal, 2011 , vol. 17, # 41 p. 11553 - 11558

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Citation Number: 23

Abstract

Abstract Intermolecular cycloadditions of conjugated dienes and nitrene precursors usually produce aziridines. A generally useful method was lacking to directly provide the [4+ 1] cycloadducts, 3-pyrrolines. We have realized this transformation by using an uniquely active catalyst, copper (II) 1, 1, 1, 5, 5, 5-hexafluoroacetylacetonate ([Cu (hfacac) 2]). The method is applicable to a wide array of dienes with good yields. When 1, 4-disubsituted dienes are ...