Homeopathic ligand-free palladium as a catalyst in the Heck reaction. A comparison with a palladacycle

…, JHM Mommers, HJW Henderickx, JG De Vries

Index: de Vries, Andre H. M.; Mulders, Jan M. C. A.; Mommers, John H. M.; Henderickx, Huub J. W.; de Vries, Johannes G. Organic Letters, 2003 , vol. 5, # 18 p. 3285 - 3288

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Citation Number: 467

Abstract

Ligand-free Pd (OAc) 2 can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol%. At higher concentrations palladium black forms and the reaction stops. The actual catalyst is monomeric. Palladacycles merely serve as a source of ligand-free palladium in Heck reactions of aryl bromides.

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