New synthesis of 3-substituted indoles using lithium trimethylsilyldiazomethane
T Miyagi, Y Hari, T Aoyama
Index: Miyagi, Takashi; Hari, Yoshiyuki; Aoyama, Toyohiko Tetrahedron Letters, 2004 , vol. 45, # 33 p. 6303 - 6305
Full Text: HTML
Citation Number: 25
Abstract
Indoles have a wide spectrum of biological activities. 1 A large number of methods for the construction of the indole nucleus have been reported. 2 Among them, the base- 3a, 3b and 3c or Lewis acid- 3d mediated, and transition-metal-catalyzed 3e, 3f, 3g, 3h and 3i cyclization of o-ethynylaniline derivatives is one of the most useful methods. However, there is still strong demand for new, versatile, and efficient methods for the construction of the indole nucleus.
Related Articles:
[Okuma, Kentaro; Yasuda, Takumi; Takeshita, Itsuki; Shioji, Kosei; Yokomori, Yoshinobu Tetrahedron, 2007 , vol. 63, # 34 p. 8250 - 8254]
Synthesis of hetero-and carbocycles by nucleophilic substitution at sp 2 carbon
[Miyauchi, Hironori; Chiba, Shunsuke; Fukamizu, Koji; Ando, Kaori; Narasaka, Koichi Tetrahedron, 2007 , vol. 63, # 26 p. 5940 - 5953]
[Rixson, James E.; Chaloner, Thomas; Heath, Charles H.; Tietze, Lutz F.; Stewart, Scott G. European Journal of Organic Chemistry, 2012 , # 3 p. 544 - 558]
[Rixson, James E.; Chaloner, Thomas; Heath, Charles H.; Tietze, Lutz F.; Stewart, Scott G. European Journal of Organic Chemistry, 2012 , # 3 p. 544 - 558]
[Rixson, James E.; Chaloner, Thomas; Heath, Charles H.; Tietze, Lutz F.; Stewart, Scott G. European Journal of Organic Chemistry, 2012 , # 3 p. 544 - 558]