The Development of Domino Reactions Incorporating the Heck Reaction: The Formation of N??Heterocycles

JE Rixson, T Chaloner, CH Heath…

Index: Rixson, James E.; Chaloner, Thomas; Heath, Charles H.; Tietze, Lutz F.; Stewart, Scott G. European Journal of Organic Chemistry, 2012 , # 3 p. 544 - 558

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Citation Number: 8

Abstract

Abstract The methodological development of a series of domino or cascade reactions affording a series of N-heterocycles is described. The rapid formation of these ring systems is in each case associated with the incorporation of a Heck reaction at either an early or a late stage of the domino process. A range of catalytic conditions and substrate modifications for optimisation of domino Tsuji–Trost/Heck, Buchwald–Hartwig/Heck and Heck/ ...

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