Tetrahedron letters

Use of hexamethylphosphoramide (HMPA) in the alkylation of aromatic amines.

E Juaristi, JD Reyna

Index: Juaristi, Eusebio; Reyna, J. Daniel Tetrahedron Letters, 1984 , vol. 25, # 33 p. 3521 - 3524

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Citation Number: 20

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Use of hexamethylphosphoramide (HMPA) in the alkylation of aromatic amines. ... The convenience of using HMPA as solvent in the mono and dialkylation of anilines was demonstrated through the study of the reaction of p-toluidine with alkyl halides, tosylates and epoxides.

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