Palladium catalyzed N-alkylation of amines with alcohols
Y Zhang, X Qi, X Cui, F Shi, Y Deng
Index: Zhang, Yan; Qi, Xiujuan; Cui, Xinjiang; Shi, Feng; Deng, Youquan Tetrahedron Letters, 2011 , vol. 52, # 12 p. 1334 - 1338
Full Text: HTML
Citation Number: 73
Abstract
An iron oxide immobilized palladium catalyst was prepared for the N-alkylation of amines with alcohols under base and organic ligand free conditions. Applying the optimized reaction conditions, the coupling reactions of amines and alcohols with various structures could be realized with up to 99% isolated yields. The catalysts were studied by XRD, BET, and XPS and the mechanism was studied by DFT calculations.
Related Articles:
[Shen, Qilong; Ogata, Tokutaro; Hartwig, John F. Journal of the American Chemical Society, 2008 , vol. 130, # 20 p. 6586 - 6596]
[Shen, Qilong; Ogata, Tokutaro; Hartwig, John F. Journal of the American Chemical Society, 2008 , vol. 130, # 20 p. 6586 - 6596]
Ligand??Free Copper??Catalyzed Amination of Heteroaryl Halides with Alkyl??and Arylamines
[Liu, Zhen-Jiang; Vors, Jean-Pierre; Gesing, Ernst R. F.; Bolm, Carsten Advanced Synthesis and Catalysis, 2010 , vol. 352, # 18 p. 3158 - 3162]
Inhibition of nucleoside transport proteins by C 8-alkylamine-substituted purines
[Kanie, Kiyoshi; Mizuno, Katsuya; Kuroboshi, Manabu; Hiyama, Tamejiro Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 8 p. 1973 - 1991]
[Wallace, Karl J.; Belcher, Warwick J.; Turner, David R.; Syed, Kauser F.; Steed, Jonathan W. Journal of the American Chemical Society, 2003 , vol. 125, # 32 p. 9699 - 9715]