N. omega.-Alkoxycarbonylation of. alpha.,. omega.-diamino acids with 2-(trimethylsilyl) ethyl 4-nitrophenyl carbonate
A Rosowsky, JE Wright
Index: Rosowsky, Andre; Wright, Joel E. Journal of Organic Chemistry, 1983 , vol. 48, # 9 p. 1539 - 1541
Full Text: HTML
Citation Number: 43
Abstract
In connection with a larger project in peptide synthesis, we had a need for Nu-protected derivatives of a, w-diamino acids from which the protecting group could be cleaved under mild neutral conditions. A further requirement was that the protecting group had to be compatible with both benzyloxycarbonyl (Z) and tert-butyloxycarbonyl (Boc) groups. The [2- (trimethylsilyl) ethoxy] carbonyl (Teoc) group,'+ which is easily cleaved at room ...
Related Articles:
[Soderquist, John A.; Brown, Herbert C. Journal of Organic Chemistry, 1980 , vol. 45, # 18 p. 3571 - 3578]
The asymmetric hydroboration of simple alkenylsilanes: chiral α-silylalkyl-boranes and alcohols
[Soderquist, John A.; Lee, Shwn-Ji Hwang Tetrahedron, 1988 , vol. 44, # 13 p. 4033 - 4042]
[Davis, Dennis D.; Jacocks, Henry M. Journal of Organometallic Chemistry, 1981 , vol. 206, # 1 p. 33 - 47]
A convenient synthesis of β-(trimethylsilyl) ethanol
[Mancini, Michael L.; Honek, John F. Tetrahedron Letters, 1982 , vol. 23, # 32 p. 3249 - 3250]
Prepation of some α-and β-hydroxyalkyl silicon compounds
[Kumada,M. et al. Journal of Organometallic Chemistry, 1966 , vol. 6, p. 490 - 495]