Enantioselective Synthesis of Spirobarbiturate-Cyclohexenes through Phosphine-Catalyzed Asymmetric [4+ 2] Annulation of Barbiturate-Derived Alkenes with …

…, Y Liu, C Yuan, GP Wang, SF Zhu, Y Wu, B Wang…

Index: Wang, Zhao-Gang; Lu, Ming RSC Advances, 2014 , vol. 4, # 3 p. 1234 - 1240

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Abstract

An enantioselective synthesis of pharmaceutically important spirobarbiturates has been achieved via spirocyclic chiral phosphine-catalyzed asymmetric [4+ 2] annulation of barbiturate-derived alkenes with allenoates. With the use of this tool, various

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