Chemistry Letters

Lewis base-catalyzed alkynylation of carbonyl compounds with trimethylsilylacetylenes

T Kitazawa, T Minowa, T Mukaiyama

Index: Kitazawa, Takayuki; Minowa, Tomofumi; Mukaiyama, Teruaki Chemistry Letters, 2006 , vol. 35, # 9 p. 1002 - 1003

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Citation Number: 26

Abstract

Alkynylation of carbonyl compounds with trimethylsilylacetylenes in the presence of a catalytic amount of Lewis bases such as acetate or phenoxide anion is described. The alkynylation proceeded under mild conditions and afforded the corresponding propargyl alcohols in good to excellent yields.

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