Achieving control over the branched/linear selectivity in palladium-catalyzed allylic amination
I Dubovyk, IDG Watson, AK Yudin
Index: Dubovyk, Igor; Watson, Iain D. G.; Yudin, Andrei K. Journal of Organic Chemistry, 2013 , vol. 78, # 4 p. 1559 - 1575
Full Text: HTML
Citation Number: 18
Abstract
Palladium-catalyzed reaction of unsymmetrical allylic electrophiles with amines gives rise to regioisomeric allylic amines. We have found that linear products result from the thermodynamically controlled isomerization of the initially formed branched products. The ...
Related Articles:
[Cooper; Lucas; Taylor; Ward; Williamson Synthesis, 2001 , # 4 p. 621 - 625]
[Arnold, Jeffrey S.; Cizio, Gregory T.; Nguyen, Hien M. Organic Letters, 2011 , vol. 13, # 20 p. 5576 - 5579]
[Arnold, Jeffrey S.; Cizio, Gregory T.; Nguyen, Hien M. Organic Letters, 2011 , vol. 13, # 20 p. 5576 - 5579]
A new synthesis of secondary allylic aliphatic and aromatic amines
[Spaltenstein, Andreas; Carpino, Philip A.; Hopkins, Paul B. Tetrahedron Letters, 1986 , vol. 27, # 2 p. 147 - 150]
[Cooper; Lucas; Taylor; Ward; Williamson Synthesis, 2001 , # 4 p. 621 - 625]