Ligand-Induced Acceleration of the Intramolecular [3+ 2] Cycloaddition between Alkynes and Alkylidenecyclopropanes
J Durán, M Gulías, L Castedo, JL Mascareñas
Index: Duran, Juan; Gulias, Moises; Castedo, Luis; Mascarenas, Jose L. Organic Letters, 2005 , vol. 7, # 25 p. 5693 - 5696
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Citation Number: 38
Abstract
Bulky phosphite L6 and several sterically robust phosphoramidites are excellent ligands for promoting the Pd-catalyzed [3+ 2] intramolecular cycloaddition between alkylidenecyclopropanes and alkynes. The use of these ligands allows for low catalyst loadings and facilitates the otherwise sluggish cycloaddition of hept-6- ynylidenecyclopropane systems.
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