8-epi-Chlorajapolide F

Modify Date: 2024-01-06 22:14:33

8-epi-Chlorajapolide F Structure
8-epi-Chlorajapolide F structure
Common Name 8-epi-Chlorajapolide F
CAS Number 863301-69-3 Molecular Weight 276.328
Density 1.3±0.1 g/cm3 Boiling Point 454.2±45.0 °C at 760 mmHg
Molecular Formula C16H20O4 Melting Point N/A
MSDS N/A Flash Point 169.9±22.2 °C

 Use of 8-epi-Chlorajapolide F


8-epi-Chlorajapolide F (compound 1) a sesquiterpene that can be isolated from the aboveground part of the Chloranthus japonicus. 8-epi-Chlorajapolide has few cytotoxic to human cancer cell lines NCI-H460 and SMMC-7721 (IC50s>50 μg/mL)[1].

 Names

Name (4aS,5aS,6aR,6bS,7S,7aS)-7-Hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-4a,5,5a,6,6a,6b,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
Synonym More Synonyms

 8-epi-Chlorajapolide F Biological Activity

Description 8-epi-Chlorajapolide F (compound 1) a sesquiterpene that can be isolated from the aboveground part of the Chloranthus japonicus. 8-epi-Chlorajapolide has few cytotoxic to human cancer cell lines NCI-H460 and SMMC-7721 (IC50s>50 μg/mL)[1].
Related Catalog
References

[1]. Zhang M, et al. Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities. Fitoterapia. 2012 Dec;83(8):1604-9.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 454.2±45.0 °C at 760 mmHg
Molecular Formula C16H20O4
Molecular Weight 276.328
Flash Point 169.9±22.2 °C
Exact Mass 276.136169
LogP 1.43
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.583

 Synonyms

Cycloprop[2,3]indeno[5,6-b]furan-2(4H)-one, 4a,5,5a,6,6a,6b,7,7a-octahydro-7-hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-, (4aS,5aS,6aR,6bS,7S,7aS)-
(4aS,5aS,6aR,6bS,7S,7aS)-7-Hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-4a,5,5a,6,6a,6b,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one