Insulin-like growth factor II
Modify Date: 2024-04-05 20:17:37
Insulin-like growth factor II structure
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Common Name | Insulin-like growth factor II | ||
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| CAS Number | 67763-97-7 | Molecular Weight | 631.68 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H45N7O11 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Insulin-like growth factor IIInsulin-like growth factor II (IGF-2) is the principal somatomedin of human serum. Insulin-like growth factor II exerts permissive and direct effects on neurite outgrowth and enhances survival of sympathetic and sensory neurons[1][2]. |
| Name | human igf-ii |
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| Description | Insulin-like growth factor II (IGF-2) is the principal somatomedin of human serum. Insulin-like growth factor II exerts permissive and direct effects on neurite outgrowth and enhances survival of sympathetic and sensory neurons[1][2]. |
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| Related Catalog | |
| In Vitro | Insulin-like growth factor II (IGF-2) (1-100 ng/mL; 24 h) 在 SH-SY5Y 细胞中以剂量依赖的方式显著增加了轴突承载细胞的百分比[2]。 Insulin-like growth factor II (IGF-2) (50 ng/mL; 1-24 h) 和 IGFBP2 联合使用增强了早期 IGF-1R 相关信号[2]。 Western Blot Analysis[2] Cell Line: SH-SY5Y cells Concentration: 50 ng/mL, alone or in combination with 50 ng/mL IGFBP2 Incubation Time: 1, 6, 12, or 24 h Result: Co-treatment increased IGF-1R phosphorylation within 1 h. Increased phosphorylated Akt (s473) within 12 h. Increased production of NF-L after 24 h. |
| References |
| Molecular Formula | C26H45N7O11 |
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| Molecular Weight | 631.68 |
| Appearance of Characters | lyophilized powder |
| Storage condition | −20°C |
| WGK Germany | 3 |
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| RTECS | NM8906000 |