Hainantoxin-IV

Modify Date: 2024-04-09 10:47:30

Hainantoxin-IV Structure
Hainantoxin-IV structure
Common Name Hainantoxin-IV
CAS Number 651782-02-4 Molecular Weight 3987.53
Density N/A Boiling Point N/A
Molecular Formula C166H257N53O50S6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hainantoxin-IV


Hainantoxin-IV is a specific antagonist of Sodium Channel, targeting to tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels. His28 and Lys32 are the key resiudes of Hainantoxin-IV for binding with target, while Hainantoxin-IV adopts an inhibitor cystine knot motif[1].

 Names

Name Hainantoxin-IV

 Hainantoxin-IV Biological Activity

Description Hainantoxin-IV is a specific antagonist of Sodium Channel, targeting to tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels. His28 and Lys32 are the key resiudes of Hainantoxin-IV for binding with target, while Hainantoxin-IV adopts an inhibitor cystine knot motif[1].
Related Catalog
References

[1]. Liu Y, et al. A positively charged surface patch is important for hainantoxin-IV binding to voltage-gated sodium channels. J Pept Sci. 2012 Oct;18(10):643-9.  

 Chemical & Physical Properties

Molecular Formula C166H257N53O50S6
Molecular Weight 3987.53
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