3’-O-(2-Methoxyethyl)-2-thiouridine

Modify Date: 2025-08-25 10:44:53

3’-O-(2-Methoxyethyl)-2-thiouridine Structure
3’-O-(2-Methoxyethyl)-2-thiouridine structure
Common Name 3’-O-(2-Methoxyethyl)-2-thiouridine
CAS Number 647839-20-1 Molecular Weight 318.35
Density N/A Boiling Point N/A
Molecular Formula C12H18N2O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-O-(2-Methoxyethyl)-2-thiouridine


3’-O-(2-Methoxyethyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

 3’-O-(2-Methoxyethyl)-2-thiouridine Biological Activity

Description 3’-O-(2-Methoxyethyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C12H18N2O6S
Molecular Weight 318.35
Exact Mass 318.08900
PSA 138.29000
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