2,3,5,6-Tetramethoxyaporphine

Modify Date: 2024-01-02 17:45:50

2,3,5,6-Tetramethoxyaporphine Structure
2,3,5,6-Tetramethoxyaporphine structure
Common Name 2,3,5,6-Tetramethoxyaporphine
CAS Number 5630-11-5 Molecular Weight 355.42800
Density 1.166g/cm3 Boiling Point 487ºC at 760 mmHg
Molecular Formula C21H25NO4 Melting Point 119ºC
MSDS N/A Flash Point 140.2ºC

 Use of 2,3,5,6-Tetramethoxyaporphine


2,3,5,6-Tetramethoxyaporphine is an antitussive agent, a medicinally valuable benzyl isoquinoline alkaloid. 2,3,5,6-Tetramethoxyaporphine can be isolated from the yellow hornpoppy, Glaucium flavum Cr. (Fam. Papaveraceae)[1][2].

 Names

Name 1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Synonym More Synonyms

 2,3,5,6-Tetramethoxyaporphine Biological Activity

Description 2,3,5,6-Tetramethoxyaporphine is an antitussive agent, a medicinally valuable benzyl isoquinoline alkaloid. 2,3,5,6-Tetramethoxyaporphine can be isolated from the yellow hornpoppy, Glaucium flavum Cr. (Fam. Papaveraceae)[1][2].
Related Catalog
References

[1]. Mohamed ME, et al. Plant germination and production of callus from the yellow hornpoppy (Glaucium flavum): the first stage of micropropagation. Pharmazie. 2014 Sep;69(9):715-20.  

[2]. Redpath JB, et al. Double-blind comparison of the respiratory and sedative effects of codeine phosphate and (+/-)-glaucine phosphate in human volunteers. Br J Clin Pharmacol. 1982 Oct;14(4):555-8.  

 Chemical & Physical Properties

Density 1.166g/cm3
Boiling Point 487ºC at 760 mmHg
Melting Point 119ºC
Molecular Formula C21H25NO4
Molecular Weight 355.42800
Flash Point 140.2ºC
Exact Mass 355.17800
PSA 40.16000
LogP 3.41100
Index of Refraction 1.575

 Synonyms

(1)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo(de,g)quinoline
(+/-)-glaucine
lauroscholtzine
1,2,9,10-tetramethoxyaporphine
rac-1,2,9,10-tetramethoxy-6-methyl-aporphane
glaucine phosphate
tussiglaucin
(+/-)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline