2,3,5,6-Tetramethoxyaporphine

Names

[ Name ]:
2,3,5,6-Tetramethoxyaporphine

[Synonym ]:
(1)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo(de,g)quinoline
(+/-)-glaucine
lauroscholtzine
1,2,9,10-tetramethoxyaporphine
rac-1,2,9,10-tetramethoxy-6-methyl-aporphane
glaucine phosphate
tussiglaucin
(+/-)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline

Biological Activity

[Description]:

2,3,5,6-Tetramethoxyaporphine is an antitussive agent, a medicinally valuable benzyl isoquinoline alkaloid. 2,3,5,6-Tetramethoxyaporphine can be isolated from the yellow hornpoppy, Glaucium flavum Cr. (Fam. Papaveraceae)[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Mohamed ME, et al. Plant germination and production of callus from the yellow hornpoppy (Glaucium flavum): the first stage of micropropagation. Pharmazie. 2014 Sep;69(9):715-20.

[2]. Redpath JB, et al. Double-blind comparison of the respiratory and sedative effects of codeine phosphate and (+/-)-glaucine phosphate in human volunteers. Br J Clin Pharmacol. 1982 Oct;14(4):555-8.

Chemical & Physical Properties

[ Density]:
1.166g/cm3

[ Boiling Point ]:
487ºC at 760 mmHg

[ Melting Point ]:
119ºC

[ Molecular Formula ]:
C₂₁H₂₅NO₄

[ Molecular Weight ]:
355.42800

[ Flash Point ]:
140.2ºC

[ Exact Mass ]:
355.17800

[ PSA ]:
40.16000

[ LogP ]:
3.41100

[ Index of Refraction ]:
1.575

Precursor & DownStream

Precursor

DownStream

Related Compounds

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