guanosine 5'-diphosphate sodium salt

Modify Date: 2024-01-02 21:58:51

guanosine 5'-diphosphate sodium salt Structure
guanosine 5'-diphosphate sodium salt structure
Common Name guanosine 5'-diphosphate sodium salt
CAS Number 43139-22-6 Molecular Weight 465.18200
Density N/A Boiling Point N/A
Molecular Formula C10H14N5NaO11P2 Melting Point N/A
MSDS USA Flash Point N/A

 Use of guanosine 5'-diphosphate sodium salt


Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].

 Names

Name guanosine 5'-diphosphate sodium salt
Synonym More Synonyms

 guanosine 5'-diphosphate sodium salt Biological Activity

Description Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418.

[2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.

 Chemical & Physical Properties

Molecular Formula C10H14N5NaO11P2
Molecular Weight 465.18200
Exact Mass 465.00600
PSA 275.02000
Storage condition 20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

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 Synonyms

guanosine 5'-diphosphate sodium salt,Type I
GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT
guanosine 5'-diphosphate sodium type I
5'-GDP 3NA
GUANOSINE-5'-DIPHOSPHATE SODIUM SALT ULTRA PURE GRADE
Guanosine-5''-diphosphoric acid monosodium salt