1-Methylhistamine-d3 dihydrochloride

Modify Date: 2024-01-30 12:34:31

1-Methylhistamine-d3 dihydrochloride Structure
1-Methylhistamine-d3 dihydrochloride structure
Common Name 1-Methylhistamine-d3 dihydrochloride
CAS Number 344299-49-6 Molecular Weight 201.11200
Density N/A Boiling Point N/A
Molecular Formula C6H10Cl2D3N3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-Methylhistamine-d3 dihydrochloride


1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride)[1]. 1-Methylhistamine dihydrochloride is a histamine metabolite[2].

 Names

Name n-tau-methyl-d3-histamine 2hcl
Synonym More Synonyms

 1-Methylhistamine-d3 dihydrochloride Biological Activity

Description 1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride)[1]. 1-Methylhistamine dihydrochloride is a histamine metabolite[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Saito K, et al. Determination of urinary excretion of histamine and 1-methylhistamine by liquid chromatography. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):270-5.  

 Chemical & Physical Properties

Molecular Formula C6H10Cl2D3N3
Molecular Weight 201.11200
Exact Mass 200.06700
PSA 43.84000
LogP 2.22560

 Synonyms

Nt-Methyl-d3-histaMine 2HCl
N-Methyl-D3-histamineHCl
NT-METHYL-D3-HISTAMINE DIHYDROCHLORIDE
N'-Methyl-D3-histamine2HCl