Sirtuin modulator 4

Modify Date: 2024-04-03 22:51:25

Sirtuin modulator 4 structure	Common Name	Sirtuin modulator 4
	CAS Number	327104-77-8	Molecular Weight	318.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₀N₂O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Sirtuin modulator 4

Sirtuin modulator 4 (compound 12) is a sirtuin modulator. Sirtuin modulator 4 shows inhibitory effect to SIRT1 with an EC50 value of 51-100 μM. Sirtuin modulator 4 may be used for the research of increasing the lifespan of a cell, and preventing a wide variety of diseases and disorders including, for example, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, inflammation and cancer[1].

Name	WAY-603231
Synonym	More Synonyms

Description	Sirtuin modulator 4 (compound 12) is a sirtuin modulator. Sirtuin modulator 4 shows inhibitory effect to SIRT1 with an EC50 value of 51-100 μM. Sirtuin modulator 4 may be used for the research of increasing the lifespan of a cell, and preventing a wide variety of diseases and disorders including, for example, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, inflammation and cancer[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	SIRT1:51-100 μM (EC50)
In Vitro	Sirtuin modulator 4 (0.7-100 μM) inhibits SIRT1 with an EC50 value of 51-100 μM[1].
References	[1]. Milburn Michael, et al. Fused heterocyclic compounds and their use as sirtuin modulators. US7998974. 2011.

Molecular Formula	C₁₈H₁₀N₂O₂S
Molecular Weight	318.35

2-Benzothiazoleacetonitrile, α-(2-benzofuranylcarbonyl)-

Sirtuin modulator 4

Use of Sirtuin modulator 4

Names

Sirtuin modulator 4 Biological Activity

Chemical & Physical Properties

Synonyms