SIRT5 inhibitor 7
Modify Date: 2025-08-27 18:15:46
SIRT5 inhibitor 7 structure
|
Common Name | SIRT5 inhibitor 7 | ||
|---|---|---|---|---|
| CAS Number | 2951090-00-7 | Molecular Weight | 582.12 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H32ClN7O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SIRT5 inhibitor 7SIRT5 inhibitor 7 (compound 58) is a substrate-competitive and selective SIRT5 inhibitor with anti-inflammatory activity. SIRT5 inhibitor 7 has renal protective effects and regulates protein succinylation and the release of pro-inflammatory cytokines. SIRT5 inhibitor 7 has in vivo activity in AKI mouse models of lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury[1]. |
| Name | SIRT5 inhibitor 7 |
|---|
| Description | SIRT5 inhibitor 7 (compound 58) is a substrate-competitive and selective SIRT5 inhibitor with anti-inflammatory activity. SIRT5 inhibitor 7 has renal protective effects and regulates protein succinylation and the release of pro-inflammatory cytokines. SIRT5 inhibitor 7 has in vivo activity in AKI mouse models of lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 310 nM (SIRT5)[1] |
| References |
| Molecular Formula | C28H32ClN7O3S |
|---|---|
| Molecular Weight | 582.12 |
| InChIKey | YVUGRSDTNXBWNT-FQEVSTJZSA-N |
| SMILES | O=C(O)CCNC(=S)NCCCNc1nc(Nc2ccccc2Cl)ncc1C(=O)N1CCC(c2ccccc2)C1 |