Tubulin inhibitor 33

Modify Date: 2025-08-26 13:46:04

Tubulin inhibitor 33 Structure
Tubulin inhibitor 33 structure
Common Name Tubulin inhibitor 33
CAS Number 2944462-67-1 Molecular Weight 414.46
Density N/A Boiling Point N/A
Molecular Formula C24H22N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tubulin inhibitor 33


Tubulin inhibitor 33, a tubulin polymerization inhibitor, inhibits tubulin polymerization in a dose-dependent manner with an IC50 of 9.05 μM. Tubulin inhibitor 33 has antitumor effects and induces cell apoptosis that can be used for antitumor research[1].

 Names

Name Tubulin inhibitor 33

 Tubulin inhibitor 33 Biological Activity

Description Tubulin inhibitor 33, a tubulin polymerization inhibitor, inhibits tubulin polymerization in a dose-dependent manner with an IC50 of 9.05 μM. Tubulin inhibitor 33 has antitumor effects and induces cell apoptosis that can be used for antitumor research[1].
Related Catalog
Target

IC50: 9.05 μM (tubulin)[1]

References

[1]. Ren Y, et.al. X-ray Crystal Structure-Guided Discovery of Novel Indole Analogues as Colchicine-Binding Site Tubulin Inhibitors with Immune-Potentiating and Antitumor Effects against Melanoma. J Med Chem. 2023 May 25;66(10):6697-6714.  

 Chemical & Physical Properties

Molecular Formula C24H22N4O3
Molecular Weight 414.46
InChIKey LCQATVJMJZBCON-UHFFFAOYSA-N
SMILES COc1cc(-c2nccc3[nH]c(-c4cccc5c4ccn5C)nc23)cc(OC)c1OC
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