Antimalarial agent 16
Modify Date: 2025-08-25 10:37:24
Antimalarial agent 16 structure
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Common Name | Antimalarial agent 16 | ||
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| CAS Number | 2773408-33-4 | Molecular Weight | 516.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H32N2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antimalarial agent 16Antimalarial agent 16 (Compound 4h) is a parasite inhibitor. Antimalarial agent 16 shows antimalarial activity, and can inhibit P. falciparum parasite growth (IC50=2.0 nM)[1]. |
| Name | Antimalarial agent 16 |
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| Description | Antimalarial agent 16 (Compound 4h) is a parasite inhibitor. Antimalarial agent 16 shows antimalarial activity, and can inhibit P. falciparum parasite growth (IC50=2.0 nM)[1]. |
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| Related Catalog | |
| Target |
IC50: 2.0 nM (P. falciparum)[1] |
| In Vivo | Antimalarial agent 16 (i.p.; 40 or 200 mg/kg; once daily; 4 days) exhibits significant in vivo antimalarial effects[1]. Animal Model: Plasmodium berghei (P. berghei) ANKA infected ICR mouse[1] Dosage: 40 or 200 mg/kg Administration: Intraperitoneal injection; 40 or 200 mg/kg; once daily; 4 days Result: Inhibited malaria parasite growth effectively and retained parasitemia levels until day 8 post-infection at a dose of 40 mg/kg, attenuated parasitemia levels until day 8. Maintained survival rates until day 11 post-infection, but the rates decreased rapidly after day 11 at a dose of 40 mg/kg, observed a significant enhancement in survival a dose of 200 mg/kg. |
| References |
| Molecular Formula | C30H32N2O6 |
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| Molecular Weight | 516.58 |