15641-17-5

15641-17-5 structure

Name: Antiproliferative agent-16
Chemical Name: WAY-313137
CAS Number: 15641-17-5
Molecular Formula: C₁₇H₁₅N₃O
Molecular Weight: 277.32
Catalog: Research Areas Cancer
Create Date: 2023-03-06 16:57:35
Modify Date: 2024-01-10 19:39:35
Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells)[1].

Name	WAY-313137
Synonyms	MFCD00412076 N'-[(E)-1H-Indol-3-ylmethylene]-2-phenylacetohydrazide Benzeneacetic acid, 2-[(1E)-1H-indol-3-ylmethylene]hydrazide

Description	Antiproliferative agent-16 is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Antiproliferative agent-16 (compound 18f) 显示出对 DU145、LnCaP、MDA-MB231、MCF7 和 PaCa2 癌细胞的细胞毒性，IC50 值分别为 115.1 μM、51.63 μM、300.8 μM、6.94 μM、和 91.18 μM[1]。
References	[1]. Swapna Sundaree, et al. Synthesis and anticancer activity study of indolyl hydrazide-hydrazones. Med Chem Res 25, 941-950 (2016).