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956928-33-9

956928-33-9 structure

956928-33-9 structure

Name: Antimalarial agent 15
Chemical Name: Antimalarial agent 15
CAS Number: 956928-33-9
Molecular Formula: C₂₉H₃₀N₂O₆
Molecular Weight: 502.56
Catalog: Research Areas Infection
Create Date: 2022-09-16 18:55:29
Modify Date: 2025-08-27 11:12:56
Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM)[1].

Name	Antimalarial agent 15

Description	Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM)[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology
Target	IC50: 20 nM (P. falciparum 3D7)[1]
In Vitro	Antimalarial agent 15 shows no cytotoxicity against mammalian cells or affects the growth of bacteria and fungi up to 30 μM[1].
References	[1]. Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:116830.

Molecular Formula	C₂₉H₃₀N₂O₆
Molecular Weight	502.56

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