CD33 splicing modulator 1 hydrochloride

Modify Date: 2025-08-27 09:51:53

CD33 splicing modulator 1 hydrochloride Structure
CD33 splicing modulator 1 hydrochloride structure
Common Name CD33 splicing modulator 1 hydrochloride
CAS Number 2762547-06-6 Molecular Weight 480.96
Density N/A Boiling Point N/A
Molecular Formula C25H26ClFN6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CD33 splicing modulator 1 hydrochloride


CD33 splicing modulator 1 (Compound 1) hydrochloride is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 hydrochloride increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 hydrochloride has the potential for the research of neurodegenerative disease including Alzheimer's disease[1].

 Names

Name CD33 splicing modulator 1 hydrochloride

 CD33 splicing modulator 1 hydrochloride Biological Activity

Description CD33 splicing modulator 1 (Compound 1) hydrochloride is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 hydrochloride increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 hydrochloride has the potential for the research of neurodegenerative disease including Alzheimer's disease[1].
Related Catalog
References

[1]. Chappie TA, et al. Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators. ACS Med Chem Lett. 2022;13(1):55-62.  

 Chemical & Physical Properties

Molecular Formula C25H26ClFN6O
Molecular Weight 480.96
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