DGKα-IN-2

DGKα-IN-2 structure	Common Name	DGKα-IN-2
	CAS Number	2648556-92-5	Molecular Weight	461.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₂F₃N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DGKα-IN-2

DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.

Name	DGKα-IN-2

Description	DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	0.9 nM (DGKα)
References	[1]. Schmees, Norbert, et al. Preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. WO2021105115.

Molecular Formula	C₂₃H₂₂F₃N₃O₄
Molecular Weight	461.43
InChIKey	AETHHGASMIIOSO-UHFFFAOYSA-N
SMILES	Cn1c(=O)c(C(N)=O)c(N2CCC(Oc3ccc(OC(F)(F)F)cc3)CC2)c2ccccc21

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DGKα-IN-2

Use of DGKα-IN-2

Names

DGKα-IN-2 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.