CB2R probe 1

Modify Date: 2024-03-31 11:08:28

CB2R probe 1 structure	Common Name	CB2R probe 1
	CAS Number	2634714-79-5	Molecular Weight	594.74
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₆H₄₂N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CB2R probe 1

CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells[1].

Name	CB2R probe 1

Description	CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	cannabinoid type-2 receptors:130 nM (Ki)
In Vitro	CB2R probe 1 (compound 28) (100 nM; 24 h) shows low cytotoxicity with IC50s of 1.6, 1.4, 1.4, 1.1, 2.6, 0.55, 2.0, 2.4, 2.8 nM for PANC1, U2OS, HT29, HT29-DX, U87AD, PC3, CB2R-HEK293, MCF7, MCFT-DX cells, respectively[1].
References	[1]. Spinelli F, et al. Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R). Eur J Med Chem. 2020 Feb 15;188:112037.

Molecular Formula	C₃₆H₄₂N₄O₄
Molecular Weight	594.74