3’-O-MOE-G(iBu)-2’-phosphoramidite

Modify Date: 2024-04-03 14:53:32

3’-O-MOE-G(iBu)-2’-phosphoramidite structure	Common Name	3’-O-MOE-G(iBu)-2’-phosphoramidite
	CAS Number	256224-06-3	Molecular Weight	913.99
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₇H₆₀N₇O₁₀P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3’-O-MOE-G(iBu)-2’-phosphoramidite

3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	3’-O-MOE-G(iBu)-2’-phosphoramidite

Description	3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Molecular Formula	C₄₇H₆₀N₇O₁₀P
Molecular Weight	913.99
InChIKey	BWLKVJLYUDLOLH-SBCRAQIVSA-N
SMILES	COCCOC1C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)OC(n2cnc3c(=O)[nH]c(NC(=O)C(C)C)nc32)C1OP(OCCC#N)N(C(C)C)C(C)C

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3’-O-MOE-G(iBu)-2’-phosphoramidite

Use of 3’-O-MOE-G(iBu)-2’-phosphoramidite

Names

3’-O-MOE-G(iBu)-2’-phosphoramidite Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.