3’-O-MOE-G(iBu)-2’-phosphoramidite

Modify Date: 2024-04-03 14:53:32

3’-O-MOE-G(iBu)-2’-phosphoramidite Structure
3’-O-MOE-G(iBu)-2’-phosphoramidite structure
Common Name 3’-O-MOE-G(iBu)-2’-phosphoramidite
CAS Number 256224-06-3 Molecular Weight 913.99
Density N/A Boiling Point N/A
Molecular Formula C47H60N7O10P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-O-MOE-G(iBu)-2’-phosphoramidite


3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

 Names

Name 3’-O-MOE-G(iBu)-2’-phosphoramidite

 3’-O-MOE-G(iBu)-2’-phosphoramidite Biological Activity

Description 3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

 Chemical & Physical Properties

Molecular Formula C47H60N7O10P
Molecular Weight 913.99
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