FGFR1 inhibitor-10

Modify Date: 2025-12-02 09:43:34

FGFR1 inhibitor-10 Structure
FGFR1 inhibitor-10 structure
 Common Name FGFR1 inhibitor-10
CAS Number 2426769-76-6 Molecular Weight 561.62
Density N/A Boiling Point N/A
Molecular Formula C26H30F3N7O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FGFR1 inhibitor-10


FGFR1 inhibitor-10 (Compound 4i) is an FGFR1 inhibitor (IC50: 28 nM). FGFR1 inhibitor-10 inhibits the phosphorylation of FGFR1. FGFR1 inhibitor-10 has anti-angiogenic, anti-invasion activity, and anti-tumor effect[1].

 Names

Name FGFR1 inhibitor-10

 FGFR1 inhibitor-10 Biological Activity

Description FGFR1 inhibitor-10 (Compound 4i) is an FGFR1 inhibitor (IC50: 28 nM). FGFR1 inhibitor-10 inhibits the phosphorylation of FGFR1. FGFR1 inhibitor-10 has anti-angiogenic, anti-invasion activity, and anti-tumor effect[1].
Related Catalog
Target

FGFR1

References

[1]. Li YL, et al. Design, synthesis and evaluation of novel pyrimidinylaminothiophene derivatives as FGFR1 inhibitors against human glioblastoma multiforme. Eur J Med Chem. 2023 Nov 15;260:115764.  

 Chemical & Physical Properties

Molecular Formula C26H30F3N7O2S
Molecular Weight 561.62
InChIKey QUPSSTNMTKCKSQ-UHFFFAOYSA-N
SMILES CNC(=O)c1ccsc1Nc1nc(Nc2ccc(N3CCC(N4CCOCC4)CC3)cc2)ncc1C(F)(F)F
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Chemsrc provides FGFR1 inhibitor-10(CAS#:2426769-76-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of FGFR1 inhibitor-10 are included as well.>> amp version: FGFR1 inhibitor-10

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