2426769-76-6

2426769-76-6 structure

Name: FGFR1 inhibitor-10
Chemical Name: FGFR1 inhibitor-10
CAS Number: 2426769-76-6
Molecular Formula: C₂₆H₃₀F₃N₇O₂S
Molecular Weight: 561.62
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
Create Date: 2024-07-17 12:56:48
Modify Date: 2024-07-17 12:56:48
FGFR1 inhibitor-10 (Compound 4i) is an FGFR1 inhibitor (IC50: 28 nM). FGFR1 inhibitor-10 inhibits the phosphorylation of FGFR1. FGFR1 inhibitor-10 has anti-angiogenic, anti-invasion activity, and anti-tumor effect[1].

Name	FGFR1 inhibitor-10

Description	FGFR1 inhibitor-10 (Compound 4i) is an FGFR1 inhibitor (IC50: 28 nM). FGFR1 inhibitor-10 inhibits the phosphorylation of FGFR1. FGFR1 inhibitor-10 has anti-angiogenic, anti-invasion activity, and anti-tumor effect[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR
Target	FGFR1
References	[1]. Li YL, et al. Design, synthesis and evaluation of novel pyrimidinylaminothiophene derivatives as FGFR1 inhibitors against human glioblastoma multiforme. Eur J Med Chem. 2023 Nov 15;260:115764.

Molecular Formula	C₂₆H₃₀F₃N₇O₂S
Molecular Weight	561.62