Anti-MRSA agent 3

Modify Date: 2025-08-26 21:17:08

Anti-MRSA agent 3 Structure
Anti-MRSA agent 3 structure
Common Name Anti-MRSA agent 3
CAS Number 2416909-42-5 Molecular Weight 520.38
Density N/A Boiling Point N/A
Molecular Formula C29H18BrN3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anti-MRSA agent 3


Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA[1].

 Names

Name Anti-MRSA agent 3

 Anti-MRSA agent 3 Biological Activity

Description Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA[1].
Related Catalog
Target

MIC: 0.098 μg/ml (MRSA)[1]

In Vivo Anti-MRSA agent 3 has potent efficacy at a dose of 10 mg/kg (20% survival) in a mouse peritonitis model[1].
References

[1]. Wang X, et al. Fascaplysin derivatives binding to DNA via unique cationic five-ring coplanar backbone showed potent antimicrobial/antibiofilm activity against MRSA in vitro and in vivo. Eur J Med Chem. 2022;230:114099.

 Chemical & Physical Properties

Molecular Formula C29H18BrN3O2
Molecular Weight 520.38
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.