MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

Modify Date: 2024-01-11 05:16:55

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan structure	Common Name	MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan
	CAS Number	2414254-52-5	Molecular Weight	1074.12
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₅H₆₀FN₉O₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].

Name	MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

Description	MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target	Topoisomerase I
References	[1]. Ying Hua, et al. Anti-B7H3 antibody-exatecan analog conjugate and medicinal use thereof: World Intellectual Property Organization, WO2020063673. 2020-04-02.

Molecular Formula	C₅₅H₆₀FN₉O₁₃
Molecular Weight	1074.12