Antibacterial agent 102

Modify Date: 2024-01-10 19:25:29

Antibacterial agent 102 structure	Common Name	Antibacterial agent 102
	CAS Number	2413293-65-7	Molecular Weight	651.86
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₅H₄₉N₅O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antibacterial agent 102

Antibacterial agent 102 (compound 32) possesses potent in vitro and in vivo antibacterial activity, with MICs < 0.5 μg/mL in Staphylococcus aureus (S. aureus). Antibacterial agent 102 also moderately inhibits CYP3A4 with an IC50 value of 6.148 μM. Antibacterial agent 102 can reduce Methicillin-resistant Staphylococcus aureus (MRSA) load in thigh infected mice[1].

Name	Antibacterial agent 102

Description	Antibacterial agent 102 (compound 32) possesses potent in vitro and in vivo antibacterial activity, with MICs < 0.5 μg/mL in Staphylococcus aureus (S. aureus). Antibacterial agent 102 also moderately inhibits CYP3A4 with an IC50 value of 6.148 μM. Antibacterial agent 102 can reduce Methicillin-resistant Staphylococcus aureus (MRSA) load in thigh infected mice[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Signaling Pathways >> Anti-infection >> Bacterial
Target	MIC: < 0.5 μg/mL (S. aureus)[1] IC50: 6.148 μM (CYP3A4)[1]
References	[1]. Zhang Z, et al. Design, synthesis and biological activities of novel pleuromutilin derivatives with a substituted triazole moiety as potent antibacterial agents. Eur J Med Chem. 2020;204:112604.

Molecular Formula	C₃₅H₄₉N₅O₅S
Molecular Weight	651.86

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Antibacterial agent 102

Use of Antibacterial agent 102

Names

Antibacterial agent 102 Biological Activity

Chemical & Physical Properties

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