Antibacterial agent 105

Modify Date: 2024-01-16 09:58:25

Antibacterial agent 105 Structure
Antibacterial agent 105 structure
Common Name Antibacterial agent 105
CAS Number 2364493-24-1 Molecular Weight 299.24
Density N/A Boiling Point N/A
Molecular Formula C14H9N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antibacterial agent 105


Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively[1].

 Names

Name Antibacterial agent 105

 Antibacterial agent 105 Biological Activity

Description Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively[1].
Related Catalog
In Vitro Antibacterial agent 105 (compound 17) has inhibitory effect on the growth of M. tuberculosis replicating in vitro cultured macrophages[1]. Antibacterial agent 105 (compound 17) (24 hours) has no toxicity on Vero cells line and human macrophages[1]. Antibacterial agent 105 (compound 17) has antibacterial activities against FQ resistant bacteria and XDR-TB[1].
References

[1]. Songuigama Coulibaly, et al. Phenanthrolinic analogs of quinolones show antibacterial activity against M. tuberculosis. Eur J Med Chem. 2020 Dec 1;207:112821.

 Chemical & Physical Properties

Molecular Formula C14H9N3O5
Molecular Weight 299.24
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