2364493-24-1

2364493-24-1 structure
2364493-24-1 structure
  • Name: Antibacterial agent 105
  • Chemical Name: Antibacterial agent 105
  • CAS Number: 2364493-24-1
  • Molecular Formula: C14H9N3O5
  • Molecular Weight: 299.24
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2022-08-24 17:25:46
  • Modify Date: 2024-01-16 09:58:25
  • Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively[1].

Name Antibacterial agent 105
Description Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM)。Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18,0.70,1.40,44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum,BCG, E. aerogenes and S. aureus, respectively[1].
Related Catalog
In Vitro Antibacterial agent 105 (compound 17) has inhibitory effect on the growth of M. tuberculosis replicating in vitro cultured macrophages[1]. Antibacterial agent 105 (compound 17) (24 hours) has no toxicity on Vero cells line and human macrophages[1]. Antibacterial agent 105 (compound 17) has antibacterial activities against FQ resistant bacteria and XDR-TB[1].
References

[1]. Songuigama Coulibaly, et al. Phenanthrolinic analogs of quinolones show antibacterial activity against M. tuberculosis. Eur J Med Chem. 2020 Dec 1;207:112821.

Molecular Formula C14H9N3O5
Molecular Weight 299.24
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