PAD-IN-2

Modify Date: 2023-02-18 13:14:00

PAD-IN-2 structure	Common Name	PAD-IN-2
	CAS Number	2304852-21-7	Molecular Weight	490.00
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₈ClN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PAD-IN-2

PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis[1].

Name	PAD-IN-2

Description	PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Epigenetics >> Protein Arginine Deiminase
In Vitro	PAD-IN-2 (Example-57, 1 h) inhibits PAD4 activity with an IC50 value <1 μM (determined by ammonia release biochemical assay)[1].
References	[1]. Hallur, Gurulingappa, et al. Heterocyclic compounds as pad4 inhibitors. Patent WO2019058393 A1.

Molecular Formula	C₂₇H₂₈ClN₅O₂
Molecular Weight	490.00

PAD-IN-2

Use of PAD-IN-2

Names

PAD-IN-2 Biological Activity

Chemical & Physical Properties