NWP-0476

Modify Date: 2025-09-11 12:25:08

NWP-0476 structure	Common Name	NWP-0476
	CAS Number	2290611-26-4	Molecular Weight	925.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₇H₅₃ClN₈O₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NWP-0476

NWP-0476 is BCL-2/BCL-xL inhibitor. NWP-0476 has a modified structure with fine-tuned BCL-xL activity. NWP-0476 can be used for relapsed T-acute lymphoblastic leukemia (T-ALL) research[1].

Name	NWP-0476

Description	NWP-0476 is BCL-2/BCL-xL inhibitor. NWP-0476 has a modified structure with fine-tuned BCL-xL activity. NWP-0476 can be used for relapsed T-acute lymphoblastic leukemia (T-ALL) research[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Neurological Disease
References	[1]. Saygin C, et al. Dual Targeting of Apoptotic and Signaling Pathways in T-Lineage Acute Lymphoblastic Leukemia. Clin Cancer Res. 2023 Aug 15;29(16):3151-3161.

Molecular Formula	C₄₇H₅₃ClN₈O₈S
Molecular Weight	925.49
InChIKey	AICNKYZLGPRISR-PSXMRANNSA-N
SMILES	CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NCC5COCCO5)c([N+](=O)[O-])c4)c(N4CCCOc5nc6[nH]ccc6cc54)c3)CC2)=C(c2ccc(Cl)cc2)C1

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