NWP-0476

Names

[ CAS No. ]:
2290611-26-4

[ Name ]:
NWP-0476

Biological Activity

[Description]:

NWP-0476 is BCL-2/BCL-xL inhibitor. NWP-0476 has a modified structure with fine-tuned BCL-xL activity. NWP-0476 can be used for relapsed T-acute lymphoblastic leukemia (T-ALL) research[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family
Research Areas >> Neurological Disease

[References]

[1]. Saygin C, et al. Dual Targeting of Apoptotic and Signaling Pathways in T-Lineage Acute Lymphoblastic Leukemia. Clin Cancer Res. 2023 Aug 15;29(16):3151-3161.  

Chemical & Physical Properties

[ Molecular Formula ]:
C47H53ClN8O8S

[ Molecular Weight ]:
925.49

Related Compounds

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